Terms of Use

1Introduction and Acceptance

These Terms of Use (“Terms”) constitute a legally binding agreement between you (“User”, “you”) and Toussi Investment & Innovation SAS (“Provider”, “we”, “us”) governing your access to and use of the Evidence Mastery website at evidencemastery.com and the EvidenceAi™ Suite of AI-powered tools and Digital Learning Products (collectively, the “Platform”).

By creating an account, purchasing Credits or Digital Learning Products, using any AI module, or otherwise accessing the Platform, you confirm that you have read, understood, and agree to be bound by these Terms and our Privacy Policy, which is incorporated herein by reference.

1.1 Eligibility

The Platform is intended exclusively for use by adults aged 18 years or older who are healthcare professionals, scientific researchers, regulatory affairs specialists, or professionals engaged in clinical research and evidence generation. By accepting these Terms, you represent and warrant that you meet these requirements.

1.2 Enterprise and B2B Clients

Organisations accessing the Platform under a Statement of Work (SOW) or Master Services Agreement are also bound by these Terms in addition to and to the extent not inconsistent with their contractual documents. In the event of conflict between an executed SOW and these Terms, the SOW shall prevail for the specific provisions addressed therein.

1.3 Effective Date

These Terms are effective as of the date you first access the Platform or create an account, whichever occurs first.

2Definitions

3The Platform and EvidenceAi™ Suite

The EvidenceAi™ Suite comprises specialised AI modules designed to assist pharmacoepidemiologists, biostatisticians, medical writers, and clinical researchers in the evidence generation workflow. All modules are accessible via the Platform following account registration.

The following modules are currently available or in development. Credit costs are indicative and the authoritative, current schedule is always available on the Pricing page.

3.1 Module Updates and New Releases

Provider reserves the right to add, modify, suspend, or discontinue any Module at any time. New Modules are published to the Platform and are accessible to all registered Users in accordance with the applicable credit schedule. Where a Module is materially changed in a manner that affects Credit consumption rates, Users will be notified via the Platform dashboard and email to their registered address.

3.2 Third-Party AI Processing

All AI generation within the EvidenceAi™ Suite is performed via the Anthropic API (Anthropic PBC, San Francisco, CA, USA). By submitting content to any Module, you acknowledge that your input text is transmitted to Anthropic for AI processing in accordance with Anthropic’s API Terms of Service and Privacy Policy. Provider does not store your submitted content beyond the duration of a single processing request.

4Account Registration and Access

4.1 Registration

Access to paid Modules requires registration of a personal Account using a valid professional email address. You must provide accurate, current, and complete registration information and keep it updated. One natural person may hold only one personal Account. Organisation-level accounts are governed by separate enterprise arrangements.

4.2 Account Security

You are solely responsible for maintaining the confidentiality of your login credentials. You must notify Provider immediately at contact@evidencemastery.com if you suspect unauthorised access to your Account. Provider will not be liable for any loss resulting from unauthorised use of your Account credentials.

4.3 Free Anonymous Access

Certain Modules designated as “Free” (currently: Guide Ai™) may be accessible without Account registration, subject to shared daily usage limits. Anonymous usage is subject to all provisions of these Terms, including the Acceptable Use Policy in Section 5.

4.4 Enterprise Domain Accounts

Users registering with an email address belonging to an organisation holding a valid enterprise agreement with Provider may be subject to additional usage parameters, credit allocations, and word-limit configurations established under that agreement. Such enterprise configurations shall take precedence over standard account defaults where they differ.

5Acceptable Use Policy

The Platform is provided for legitimate professional use in clinical research, evidence generation, regulatory preparation, and scientific education. The following activities are strictly prohibited and constitute grounds for immediate account suspension and legal action:

5.1 Fair Use

The Platform is designed for internal professional use in genuine clinical research and evidence generation activities. Users are expected to exercise good faith and use Modules for their intended purposes. Provider reserves the right to investigate unusual usage patterns and take proportionate action, including temporary throttling or account review, where usage appears inconsistent with these Terms.

6AI-Generated Content — Educational Purpose and No Guarantee

6.1 Nature of AI-Generated Outputs

You acknowledge and agree that:

• AI-generated Deliverables are probabilistic outputs based on patterns in training data and may contain errors, omissions, outdated information, hallucinated references, or contextually inappropriate content;
• Outputs are constrained by the quality, completeness, and clarity of the inputs you provide;
• The AI models used may have knowledge cutoff dates, may not reflect the most recent scientific literature, regulatory guidance, or methodological standards, and may not account for jurisdiction-specific requirements;
• Generated references, citations, and bibliographic information must be individually verified before any use — Provider specifically disclaims any warranty as to the accuracy or existence of any cited source.

6.2 Mandatory Human Expert Review

The following activities remain the sole and exclusive responsibility of qualified human professionals and may not be delegated to or satisfied by AI-generated Deliverables:

• Final scientific review, statistical validation, and medical writing approval;
• Regulatory strategy, submission preparation, and interactions with health authorities (EMA, FDA, ANSM, MHRA, or any other body);
• Quality assurance, GCP compliance, audit preparedness, and compliance with ICH E6(R2), ICH E9(R1), 21 CFR Part 11, EU Annex 11, and applicable national regulations;
• Medical, clinical, or public health decisions of any kind.

6.3 No Regulatory Warranty

Provider does not warrant that any Deliverable meets the specific requirements of any regulatory authority, HTA body, journal, or ethics committee. Deliverables generated by the Platform have not been reviewed or approved by any health authority. No Deliverable should be submitted to any external body without comprehensive human review, validation, and adaptation.

6.4 Quality Assurance Credit Refund (Registered Users)

Registered Users who believe a Deliverable generated on a paid Module fundamentally fails to address the core request — not on grounds of quality preference, but due to a material processing failure attributable to Provider — may request a Quality Assurance Credit Refund (QACR) within ten (10) business days of generation by emailing contact@evidencemastery.com with subject line “QACR Request — [Module Name] — [Date]”. Provider will review and respond within five (5) business days. Credit restoration (not cash refund) is the sole remedy under the QACR process. Provider’s determination is final.

7Credits, Billing and Pricing

7.1 Credit System

Access to paid Modules is governed by a Credit consumption model. Each Module execution deducts a defined number of Credits from the User’s account balance at the point of generation. The current Credit cost for each Module is always published on the Pricing page and on the Account dashboard. Credit costs are subject to change with reasonable notice per Section 3.1.

7.2 Credit Purchases

Credits may be purchased through the Platform in predefined packs. All transactions are processed securely via Stripe (Stripe, Inc., San Francisco, CA, USA). All prices are published in USD for retail purchases. Payment is due in full at the time of purchase. Credits are added to the User’s account immediately upon successful payment confirmation.

Current Credit pack pricing and volume discounts are set out on the Pricing page. Provider reserves the right to adjust Credit pack pricing at any time; the price applicable to a purchase is the price displayed at the time of that purchase.

7.3 New Account Bonus

Newly registered accounts receive a small Credit bonus upon registration, as displayed on the registration page and dashboard. This bonus is non-transferable, non-refundable, and subject to the same Credit validity conditions as purchased Credits.

7.4 Enterprise Billing

Organisations accessing the Platform under a Statement of Work are billed and invoiced in accordance with the applicable SOW. Enterprise Credit costs, tiers, and rollover provisions are governed exclusively by the SOW. These retail Credit terms apply solely to individual Users purchasing Credits directly through the Platform.

8Credit Validity, Expiry and Non-Reimbursability

8.1 Non-Reimbursability

Credits are non-refundable and have no monetary value. Under no circumstances will Provider provide cash refunds, chargebacks, or monetary compensation for unused Credits, whether upon voluntary account closure, subscription lapse, Module unavailability, or for any other reason. The sole exception is the Quality Assurance Credit Refund (QACR) process described in Section 6.4, which provides Credit restoration only, not monetary reimbursement.

8.2 Conditional Non-Expiry

Purchased Credits do not expire provided that the User:

• Maintains a registered Account on the Platform that has not been deactivated, suspended, or closed; and
• Has made at least one Credit purchase on the Platform within the preceding twenty-four (24) calendar months.

This constitutes the User’s active subscription to the EvidenceAi™ Suite for the purposes of Credit validity. There is no separate subscription fee required to maintain Credit validity, provided these conditions are met.

8.3 Grace Period upon Subscription Lapse

If a User’s subscription lapses — meaning their Account becomes inactive or they have not made any Credit purchase for a continuous period exceeding twenty-four (24) months — the following applies:

1. Provider will send a notification to the User’s registered email address thirty (30) days before the anticipated Credit forfeiture date, informing the User of the lapse and the available Grace Period;
2. A Grace Period of ninety (90) calendar days commences from the date of the notification or the date of subscription lapse, whichever is earlier;
3. During the Grace Period, the User may reactivate their subscription by making any Credit purchase, which will immediately restore full Credit validity;
4. If no reactivation occurs before the end of the Grace Period, all remaining Credits in the User’s account are permanently forfeited without compensation.

8.4 Account Closure

If a User voluntarily closes their Account or if Provider terminates an Account for violation of these Terms, all remaining Credits are immediately and permanently forfeited without compensation. No Grace Period applies in the case of termination for breach of these Terms.

8.5 Non-Transferability

Credits are personal to the registered Account to which they are assigned and may not be transferred, gifted, sold, or assigned to any other User or account under any circumstances. Credits may not be combined across multiple personal accounts.

8.6 Credit Expiry in Legacy or Trial Contexts

Credits granted as part of a promotional offer, free trial, referral programme, or equivalent may be subject to separate expiry terms disclosed at the time of grant. Where such terms conflict with this Section, the specific promotional terms shall prevail for those Credits only.

9Courses, Masterclasses and Digital Learning Products

In addition to the EvidenceAi™ Suite, the Platform offers a range of digital learning products, including online masterclasses, audio courses, and electronic books (collectively, “Digital Learning Products”). These are sold separately from Credits and governed by the specific provisions of this Section in addition to the rest of these Terms.

9.1 Scope of Digital Learning Products

Digital Learning Products currently available or in development on the Platform include:

• Masterclasses — structured online video and audio courses on pharmacoepidemiology, real-world evidence methodology, and related scientific disciplines;
• Audio courses — downloadable or streamed audio programmes forming part of a masterclass or sold as standalone learning products;
• Electronic books — digital publications in PDF or equivalent format, including the Real-World Evidence book series published by the Elixir Institute.

The catalogue of available Digital Learning Products, their descriptions, and their individual prices are displayed on the Platform at the time of purchase. Provider reserves the right to add, modify, or discontinue any Digital Learning Product at any time. Access to a product already purchased is not affected by its subsequent removal from the catalogue.

9.2 Purchasing and Payment

Digital Learning Products are purchased individually at the price displayed at the time of purchase. All transactions are processed securely via Stripe (Stripe, Inc., San Francisco, CA, USA). All prices are stated in USD unless otherwise indicated at the time of purchase. Access is granted to the purchasing Account immediately upon successful payment confirmation. Digital Learning Product purchases are personal to the purchasing Account and cannot be transferred to another Account.

9.3 Right of Withdrawal — Waiver for Digital Content

Under EU Directive 2011/83/EU (Article 16(m)) and French consumer law (Article L221-28 12° of the Code de la Consommation), the statutory fourteen (14) day right of withdrawal does not apply to digital content not supplied on a tangible medium — including audio courses, video masterclasses, and electronic books — where:

1. The User has expressly requested that performance (delivery of the digital content or commencement of access) begin before the expiry of the withdrawal period; and
2. The User has acknowledged at the point of purchase that this express request results in the loss of the right of withdrawal.

By completing a purchase of any Digital Learning Product on the Platform, you expressly request immediate access and acknowledge that you waive your right of withdrawal in accordance with the above. This acknowledgement is confirmed by a dedicated checkbox at the time of purchase, which must be ticked before the transaction can be completed.

9.4 Non-Reimbursability of Digital Learning Products

All sales of Digital Learning Products are final. Provider will not issue cash refunds, credit notes, EvidenceAi™ Credits, or any other form of compensation for any Digital Learning Product purchase once access has been granted, regardless of whether the reason is:

• Change of mind or failure to use or complete the content;
• Dissatisfaction with content quality, style, depth, or scope;
• Duplicate purchase;
• Technical difficulties on the User’s own device, browser, or network (where the Platform itself has been confirmed as operational);
• Voluntary account closure after purchase;
• Account suspension or termination for breach of these Terms;
• Any other reason not arising from a material technical failure attributable solely and directly to Provider.

The sole exception is where a purchased Digital Learning Product is entirely and persistently inaccessible due to a technical failure attributable solely to Provider and which Provider is unable to remediate within a reasonable period. In such case, Provider may, at its sole discretion, offer a re-credit to the User’s Account or a monetary reimbursement. Such determination is entirely at Provider’s discretion and does not constitute a general right to reimbursement.

9.5 Access Duration and Account Linkage

Access to purchased Digital Learning Products is linked to the User’s Account and is granted for the lifetime of that Account, subject to these Terms. Provider does not guarantee the indefinite availability of any specific Digital Learning Product but will use reasonable efforts to maintain access to purchased content for the duration of the Account.

If an Account is voluntarily closed or terminated by Provider for breach of these Terms, access to all Digital Learning Products associated with that Account is immediately revoked without compensation or refund.

9.6 Intellectual Property in Learning Content

All content within Digital Learning Products — including audio recordings, video, scripts, course materials, illustrations, and text — is the exclusive intellectual property of Toussi Investment & Innovation SAS and is protected by French and international copyright law. Purchase of a Digital Learning Product grants the User a personal, non-exclusive, non-transferable licence to access and use the content for their own professional development purposes only.

You may not reproduce, redistribute, broadcast, publicly perform, resell, sub-license, or share access to any element of a Digital Learning Product, in whole or in part, by any means, whether for commercial gain or otherwise. Violation of this provision constitutes grounds for immediate Account termination and may give rise to claims for copyright infringement.

10Intellectual Property and Trademarks

10.1 Provider Intellectual Property

The Platform, including all software, source code, algorithms, prompt architectures, output formatting logic, database structures, Module designs, user interface elements, visual design, and documentation, is the exclusive intellectual property of Toussi Investment & Innovation SAS and is protected by French and international copyright, patent, and trade secret law. No right, title, or interest in any Platform intellectual property is transferred to Users under these Terms.

10.2 Trademarks

The following names and marks are registered or unregistered trademarks of Toussi Investment & Innovation SAS and may not be used without prior written consent:

• Guide Ai™
• Explore Ai™
• Concept Ai™
• Feasibility Ai™
• Protocol Ai™
• SAP Ai™
• Code Ai™
• Data Ai™
• Analyze Ai™
• Report Ai™
• Manuscript Ai™
• Appraise Ai™
• Evidence Mastery™ — platform brand
• ARWDE™ — Annals of Real-World Data & Evidence

10.3 User Content and Deliverables

You retain ownership of all original content you submit to the Platform (“User Content”). You grant Provider a limited, non-exclusive, royalty-free licence to process and transmit your User Content solely for the purpose of providing the requested Module services.

Deliverables generated by the Platform are owned by you, subject to the following conditions:

• You may not represent Deliverables as the exclusive original work of a human author without appropriate AI disclosure;
• You may not use Deliverables to train, fine-tune, or benchmark external AI models;
• Your ownership of a Deliverable does not confer any ownership rights over the underlying Platform technology, prompt design, or generation methodology.

10.4 Prohibition on Reverse Engineering

You must not attempt to derive, reproduce, or reconstruct the Platform’s prompt architecture, module logic, output templates, or any other proprietary methodology through any means, including systematic analysis of Deliverable structure, format, or content.

11Data Protection and Privacy

The collection, use, and protection of personal data in connection with the Platform — including GDPR rights, international data transfers, cookie policy, and contact details for data protection enquiries — is governed exclusively by our Privacy Policy, which forms an integral part of these Terms.

12Limitation of Liability

12.1 Exclusion of Consequential Loss

Provider shall not be liable for any indirect, incidental, special, consequential, punitive, or exemplary damages arising from:

• The quality, accuracy, completeness, or suitability of any Deliverable for any purpose;
• Regulatory decisions, rejections, or outcomes arising from reliance on Platform outputs;
• Clinical, medical, or public health consequences of decisions informed by Deliverables;
• Loss of data, loss of profits, loss of business opportunity, or reputational harm;
• Platform unavailability, interruption, or technical failures;
• Unauthorised access to a User’s account by third parties;
• Inability to access a Digital Learning Product due to circumstances not attributable to Provider.

12.2 Platform Availability

Provider aims to maintain Platform availability but does not guarantee uninterrupted access. The Platform may be unavailable for scheduled maintenance, updates, or due to circumstances beyond Provider’s reasonable control. Provider will use commercially reasonable efforts to minimise downtime and communicate scheduled maintenance in advance.

12.3 Mandatory Statutory Rights

Nothing in these Terms shall limit Provider’s liability for fraud, death or personal injury caused by negligence, or any other liability that cannot be excluded or limited under applicable French law or EU consumer law.

13Termination and Suspension

13.1 Termination by User

You may close your Account at any time by contacting contact@evidencemastery.com. Upon voluntary account closure, your remaining Credits are forfeited in accordance with Section 8.4, and access to all Digital Learning Products is immediately revoked in accordance with Section 9.5. Provider will retain your data only as required by applicable law and as described in the Privacy Policy.

13.2 Suspension and Termination by Provider

Provider may immediately suspend or permanently terminate any Account, without refund of Credits or Digital Learning Product purchases, where Provider reasonably believes the User has:

• Breached any provision of these Terms, in particular Section 5 (Acceptable Use Policy);
• Submitted fraudulent payment information;
• Engaged in activities that harm or threaten the security, integrity, or reputation of the Platform;
• Misrepresented AI-generated outputs in a manner that may endanger public health or deceive a regulatory authority.

Where the nature of the breach permits, Provider will provide written notice and a reasonable opportunity to remedy the breach before exercising this right, except in cases of serious or repeated violations.

13.3 Effect of Termination

Upon termination for any reason: (a) your right to access the Platform immediately ceases; (b) all remaining Credits are forfeited without compensation; (c) access to all Digital Learning Products is immediately revoked without compensation; (d) Sections 6, 10, 12, 14, and this Section 13.3 shall survive termination indefinitely.

14Governing Law and Dispute Resolution

14.1 Applicable Law

These Terms are governed by and construed in accordance with the laws of France, without regard to its conflict of law provisions. As a French-registered company, Provider is also subject to EU consumer protection law, including Directive 2011/83/EU on consumer rights and applicable French consumer law provisions, where these apply.

14.2 Consumer Users in the EU

If you are a consumer (not acting for professional or business purposes) resident in a European Union member state, you may also benefit from mandatory consumer protection provisions of the law of your country of residence that cannot be overridden by contract. Nothing in these Terms is intended to deprive you of such protections.

14.3 Dispute Resolution

In the event of a dispute arising from these Terms, the Parties agree to first attempt resolution through good-faith negotiation. Where resolution is not achieved within thirty (30) days:

• B2B disputes: Subject to exclusive jurisdiction of the Commercial Court of Orléans (Tribunal de Commerce d’Orléans), France;
• Consumer disputes (EU residents): Subject to the jurisdiction of the competent court in the User’s place of residence, or alternatively resolved via the EU Online Dispute Resolution platform at ec.europa.eu/consumers/odr;
• French consumers: May also have recourse to a certified consumer mediator (médiateur de la consommation) pursuant to Articles L611-1 et seq. of the French Consumer Code.

15Changes to These Terms

Provider reserves the right to update or amend these Terms at any time to reflect changes in the Platform, applicable law, or business practices. The “Last updated” date at the top of this page indicates when the most recent revisions were made.

For material changes — defined as changes that affect User rights, Credit validity, Digital Learning Product refund policy, pricing policies, or the Acceptable Use Policy — Provider will provide at least thirty (30) days’ advance notice via:

• Email notification to the User’s registered address;
• A prominent notice on the Platform dashboard upon login.

Continued use of the Platform after the effective date of any updated Terms constitutes your acceptance of those updated Terms. If you do not agree to the updated Terms, you must cease using the Platform and may close your Account pursuant to Section 13.1.

16Contact and Complaints

For any questions about these Terms, to report a breach, or to exercise your rights, please contact us:

For privacy and data protection enquiries specifically, please see our Privacy Policy which contains full contact details for GDPR requests and CNIL complaints.